WEBVTT 00:01:03.730 --> 00:01:04.064 Hi, I'm 00:01:04.064 --> 00:01:07.534 Doctor Jake Hutchins from the University of Minnesota Medical Center. 00:01:08.001 --> 00:01:10.603 I’m the director of our regional acute pain program, 00:01:10.603 --> 00:01:13.606 which is the Perioperative and Interventional pain service. 00:01:13.940 --> 00:01:16.943 And today, I was doing an ITAP procedure 00:01:17.977 --> 00:01:20.080 for a patient undergoing 00:01:20.080 --> 00:01:23.850 a open hysterectomy and pelvic mass removal. 00:01:23.983 --> 00:01:25.852 53 year old female patient. 00:01:25.852 --> 00:01:29.222 So for the actual procedure, I will start with 0.25% 00:01:29.222 --> 00:01:32.225 bupivacaine with epinephrine 1 to 200,000. 00:01:32.425 --> 00:01:36.029 I'll use that to help find the space and find the correct 00:01:36.096 --> 00:01:39.099 plane in the transversus abdominis underneath the fascial plane. 00:01:39.833 --> 00:01:42.102 Once I'm ensured that I'm in the correct plane 00:01:42.102 --> 00:01:45.105 and not intravascular, then I will use 00:01:45.472 --> 00:01:50.143 30mL of a solution from the 20mL of the EXPAREL, 00:01:50.376 --> 00:01:54.481 which I've expanded to 60mL with 0.9% normal saline. 00:01:54.914 --> 00:01:59.586 I'll take 30mL of that solution and inject it on either side for the TAP. 00:01:59.853 --> 00:02:04.791 So now we'll come in with our bupivacaine quarter percent to find the actual spot. 00:02:06.893 --> 00:02:09.863 And test for intravascular injection. 00:02:18.471 --> 00:02:18.771 Okay. 00:02:18.771 --> 00:02:20.707 Give a cc there. 00:02:20.707 --> 00:02:22.609 Beautiful, stop. 00:02:22.609 --> 00:02:25.578 Now switch to the EXPAREL 00:02:25.578 --> 00:02:28.581 and we'll do three syringes or 30mL of that. 00:02:36.623 --> 00:02:36.990 Okay. 00:02:36.990 --> 00:02:39.826 Keep it in. 00:02:39.826 --> 00:02:42.228 A little bit of more pressure. 00:02:42.228 --> 00:02:42.562 Let's go. 00:02:42.562 --> 00:02:45.565 The last 10 mL of this medication. 00:02:53.273 --> 00:02:57.577 We started using EXPAREL in October of 2012. 00:02:58.044 --> 00:03:00.713 And since then we've had very good results 00:03:00.713 --> 00:03:03.750 in over 350 ITAP procedures. 00:03:04.350 --> 00:03:08.755 We've used this in a wide variety of surgical procedures in the abdomen, 00:03:09.322 --> 00:03:12.292 and have had very good results in terms of 00:03:12.525 --> 00:03:16.462 very good pain control in the recovery room, as well as pain 00:03:16.462 --> 00:03:20.633 control postoperatively for the up to 72 hours after surgery. 00:03:20.867 --> 00:03:24.037 In conjunction with EXPAREL, we tried to avoid 00:03:24.470 --> 00:03:27.273 opioids in the majority of our patients, if able. 00:03:27.273 --> 00:03:30.710 And so we'll use other non-opioid therapies to help treat 00:03:31.177 --> 00:03:34.681 our patients pain in order to minimize opioids as much as we can. 00:03:34.681 --> 00:03:38.284 And we've been very successful at that in our patient population