ERAS and multimodal protocols with EXPAREL improve postsurgical outcomes*

  • ERAS protocols are multimodal pathways for comprehensive perioperative care that help make early recovery after surgery possible by supporting preoperative organ function and reducing postsurgical stress1
    • ERAS protocols have been shown to reduce complications and morbidity rate as well as generate cost savings2,3
    • One of the key elements in ERAS protocols is use of multimodal pain management strategies to minimize opioid-based postsurgical pain control4
  • Evidence is growing that the addition of EXPAREL to ERAS protocols improves postsurgical outcomes for a variety of surgical procedures:
  • Hernia repair5
  • Breast reconstruction6
  • Lumpectomy7
  • Liver surgery8
  • Abdominal wall reconstruction9
  • Nephrectomy10
  • Thoracotomy11
  • Spinal surgery12
  • C-section13
  • TKA (total knee arthroplasty)14

Enhanced recovery protocols with multimodal analgesia reduce opioid consumption, ORAEs, and improve recovery outcomes15

Reduce pain16

Minimize ORAEs17

Reduce time to discharge18

Decrease costs19

ERAS pathways accelerate postoperative recovery and reduce general morbidity by simultaneously applying multiple interventions based on evidence20

ERAS is designed to:

Attenuate patient stress21

Maintain preoperative bodily compositions and organ function21

Integrate throughout the perioperative pathway22

Maintain physiologic function21

Facilitate (early) postsurgical recovery21

Reduce complications and LOS22

Reduce variability22

Increase value by reducing cost and improving quality of care21,22

*The clinical benefit of the decrease in opioid consumption was not demonstrated in the pivotal trials.

LOS, length of stay; ORAE, opioid-related adverse event.