EXPAREL can be administered via infiltration, interscalene brachial plexus nerve block, and fascial plane blocks to provide long-lasting non-opioid pain control

More than 14 million patients have received non-opioid EXPAREL since 2012. EXPAREL works locally at the surgical site and uses the proprietary multivesicular liposome (pMVL) technology, which encapsulates bupivacaine in a suspension of multivesicular liposomes. After injection, bupivacaine is released over time.1,2

The pMVL technology and versatility of administration enables infiltration into the surgical site to produce local analgesia, in the fascial plane to produce regional analgesia as a regional field block or as an interscalene brachial plexus nerve block. EXPAREL may be used across surgical procedures and has demonstrated improved clinical and economic outcomes.


Broad indication across surgical procedures to provide regional analgesia

Interscalene brachial plexus nerve block

Use interscalene brachial plexus nerve block in procedures such as total shoulder arthroplasty and rotator cuff surgeries

Field blocks (ie, TAP & PECS)

Use EXPAREL to provide effective regional field or interfascial plane blocks in a range of procedures

TAP, transversus abdominis plane.

The broad indication of EXPAREL affords versatility of administration

Administer as surgical site infiltration to produce local analgesia, as a field block to produce regional analgesia, or in adults, as an interscalene brachial plexus nerve block.