EXPAREL Provides Pain Relief When It Matters Most
EXPAREL in Anesthesia Specialty*
Clinical Efficacy
Manage Pain & Minimize Opioids After TKA
EXPAREL vs bupivacaine HCl in TKA (adductor canal pivotal trial)1
Superior Pain Control vs Bupivacaine HCl
cumulative pain scores (P<0.0074)
23% Fewer Opioids†
total postsurgical opioid consumption (P<0.0071)
*EXPAREL is indicated to provide analgesia
†The clinical benefit of the decrease in opioid consumption was not demonstrated in the pivotal trials
Multimodal Protocols & Results
Multimodal approaches with or without ERAS protocols have demonstrated benefits
Abdominal-Wall Field Blocks (ie, TAP)
Use a local anesthetic to provide effective regional analgesia for a range of procedures.2
Provide analgesia to the anterior abdominal wall and involve administration of a local anesthetic into the fascial plane between the transversus abdominis and internal oblique muscles.3
Approaches to
abdominal-wall field blocks
continue to evolve
TAP blocks
Originally described as a landmark-guided field block based on the lumbar triangle2
Ultrasound-guided TAP blocks
Allow visualization of the needle and local anesthetic in the plane2
Additional approaches
have been & continue to be
developed, including2,4,5:
- Subcostal TAP blocks
- Bilateral 4-point TAP blocks
- Rectus sheath blocks
- QL blocks
- ESP blocks
ESP, erector spinae plane; QL, quadratus lumborum; TAP, transversus abdominis plane.
PECS (Ultrasound-Guided Medial and Lateral Pectoralis Nerve) Block
A less invasive technique for providing analgesia after breast surgery compared with standard approaches such as thoracic epidural, paravertebral, intercostal nerve, and interpleural blocks.6,7
PECS blocks are applied in the pectoral and axillary regions, with the muscles in both regions innervated by the brachial plexus.7
In PECS I and PECS II field infiltration, ultrasound guidance can be used to identify the appropriate fascial plane(s) and to deposit local anesthetic to provide regional analgesia.6
These techniques provide effective analgesia after breast surgery and, unlike thoracic paravertebral and epidural blocks, are not associated with sympathetic blocks.6
