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EXPAREL Provides Pain Relief When It Matters Most

EXPAREL in Plastic Surgery

EXPAREL Has Been Used Across Plastic Surgeries From Abdominoplasty & Mammaplasty To Breast
& Abdominal Wall Reconstruction


In Cosmetic Procedures

4-Hour Shorter Mean Length of Stay

in obesity class I mammaplasty patients vs bupivacaine HCI (P=0.038)2*

39% Reduced Postoperative Dose of Hydromorphone

in abdominoplasty as part of TAP block vs standard nerve block (2.63 mg vs 4.31 mg; P=0.024)3†‡

In Reconstructive Procedures

24% Reduced Pain Scores at Discharge

in mammaplasty vs presurgical paravertebral block (3.2 vs 4.2; P<0.008)

47% Reduced Postsurgical Opioid Consumption

in implant-based breast reconstruction vs bupivacaine HCI (0.76 MED/h vs 1.43 MED/h; P=0.017)5‡¶

36% Reduced Length of Stay in Implant-Based Breast Reconstruction

vs bupivacaine HCI (29.8 hours vs 
46.7 hours; P=0.035)

29% Reduced Mean Total Costs in Abdominal Wall & Breast Reconstruction

procedures vs bupivacaine HCI ($28,021 vs $39,531; P=0.02)6#

*Retrospective review of reduction mammaplasty patients (N=113) treated with bupivacaine HCl (n=34) or EXPAREL (n=79)2

Pilot study in which abdominoplasty patients (N=32) received either EXPAREL with TAP block (n=16) or a combination of pararectus injections and ilioinguinal/iliohypogastric nerve blocks (n=16)3

The clinical benefit of the decrease in opioid consumption was not demonstrated in pivotal trials

§A retrospective review of patients (N=97) who underwent mastectomy with immediate tissue expander reconstruction using preoperative paravertebral block (n=53) compared with those treated with intraoperative EXPAREL infiltration (n=44)4

A prospective, randomized, single-blind trial comparing bupivacaine HCl (n=12) with EXPAREL (n=12) in patients undergoing implant-based breast reconstruction5

#A retrospective claims analysis using the Vizient Clinical Data Base/Resource Manager abstract discharge database to identify abdominal wall and breast reconstruction procedures at participating hospitals6

TAP, transversus abdominis plane.

Societies Recommend Opioid-Minimizing Pain Management Platforms


Leading medical societies recommend opioid-minimizing pain management strategies to enhance recovery after plastic surgery

ASPS

Use of multimodal approaches should be considered over the use of single agents, particularly narcotics.1

ASPS, American Society of Plastic Surgeons.

Related Resources

Clinical Study

Adductor Canal Block Study Summary

Clinical Study

Adductor Canal Block
TKA Clinical Study

Clinical Study

Sciatic Nerve Block in the Popliteal Fossa Study Summary

Clinical Study

EXPAREL vs Bupivacaine