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EXPAREL Provides Pain Relief When It Matters Most

EXPAREL in Spine Surgery

Clinical & Economic Outcomes


EXPAREL is a cost-effective option for postsurgical pain management both in the hospital and in outpatient settings

Minimally Invasive TLIF1

Medical center in Florida

  • 2.7 days shorter length of stay
  • $3,444 reduction in total cost for acute-care hospitalization*
  • 100% rate of discharge home
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Unilateral, Single-Level TLIF2

Medical center in Massachusetts

  • Significantly better pain control reported in the first 24 hours
  • 34% fewer opioids used at 12 to 24 hours‡§
  • 1.2 days shorter LOS
  • $590 lower mean total per-patient cost
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*Areas of greatest savings included a reduction in intensive care unit costs, shorter overall LOS, and decreased costs from a reduced operating room duration1

Pain was self-reported by patients using the visual analog scale. Scores recorded over the first 3 days were divided into 12-hour intervals and used to calculate the area under the curve2

Opioid consumption was measured using intravenous morphine milligram equivalent2

§The clinical benefit of the decrease in opioid consumption was not demonstrated in the clinical trials

LOS, length of stay; TLIF, transforaminal lumbar interbody fusion.

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